16 AMP binding to Website one appears to lead to allosteric activation, While binding of AMP or ADP to Site 3 appears to modulate the phosphorylation condition of Thr172.thirteen Whilst mobile ADP stages are bigger than All those of AMP, a current research has shown that AMP is really a bona fide activator that enhances LKB1-dependent Thr 172 phosp

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